Elevated serum levels of adiponectin and interlukin-28B after IFN/RIB therapy in hepatitis C virus-infected patients
نویسندگان
چکیده
منابع مشابه
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients
Hepatitis C virus (HCV) is the major etiological agent of human non-A and non-B hepatitis, affecting around 180 million people worldwide. Defensins, small cysteine-rich cationic peptides, are shown to have potent antibacterial, antiviral, and antifungal properties. Defensins can be found in both normal and microbial infected patients, at variable concentrations. Notably, viral infections are of...
متن کاملSerum Sclerostin in Hepatitis C Virus Infected Patients
BACKGROUND Sclerostin inhibits osteoblast functions, differentiations, and survival rates. As an endogenous inhibitor of the Wnt/β-catenin pathway, the sclerostin should be related to decreased bone masses, although several studies indicate opposite results. In addition, it may be related to insulin resistances and carbohydrate metabolisms, a relation shared with other markers of bone metabolis...
متن کاملImmunosuppression in hepatitis C virus-infected patients after kidney transplantation.
Hepatitis C virus (HCV) infection is an important health problem in kidney transplant recipients with a significantly higher prevalence than in the general population. Kidney transplantation remains the treatment of choice for most HCV-infected patients with end-stage kidney disease, in spite of lower patient and graft survival as compared to HCV-negative patients. Immunosuppression likely has ...
متن کاملEvaluation of IL-28B Polymorphisms and Serum IP-10 in Hepatitis C Infected Chimpanzees
In humans, clearance of hepatitis C virus (HCV) infection is associated with genetic variation near the IL-28B gene and the induction of interferon-stimulated genes, like IP-10. Also in chimpanzees spontaneous clearance of HCV is observed. To study whether similar correlations exist in these animals, a direct comparison of IP-10 and IL-28B polymorphism between chimpanzees and patients was perfo...
متن کاملElevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy.
Hepatitis C virus (HCV), a major cause of liver disease worldwide, is frequently resistant to the antiviral alpha interferon (IFN). We have recently found that the HCV NS5A protein induces expression of the proinflammatory chemokine IL-8 to partially inhibit the antiviral actions of IFN in vitro. To extend these observations, in the present study we examined the relationship between levels of I...
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ژورنال
عنوان ژورنال: The Journal of Infection in Developing Countries
سال: 2019
ISSN: 1972-2680
DOI: 10.3855/jidc.11190